Notably not the first, but the most creative of such recent devices is an app and appendix to your iPhone that measures blood sugar. Making the lives of many Type 1 and 2 diabetics much more flexible (when you leave your house, you are bound to forget your phone less often than your blood sugar monitor).
Many have been reluctant to approve and even conceive such possibility due to fear of too little medical literacy among the potential users. But that is exactly what was said about home pregnancy tests, and no birthing and health care apocalypse was witnessed upon its introduction to the market. And though the fear is very legitimate as health is something we don't want people to experiment with, most people are, believe it or not, capable of understanding medical information. Sometimes those with chronic diseases are even more informed than their caregivers given that they live with their conditions 24/7 while they only spend a small fraction of that time being in professional care. If we inform, clearly and thoughtfully, information and user will unite.
So, I predict in the next 10 and 20 years, (IF apps and iPhones are still around and the way to make these viable); you will be poking yourself with your phone. Here are three small examples.
An extra small little device which you pee on, analysing hCG values and determining if you are pregnant or not as well as monitoring hCG levels throughout the first 12 weeks.
Another device, but same app can track ovulation hormones.
Just a prick and the results are in! What are you lacking, what are you in abundance of. A lot of the times fatigue and bad immunity can just be a result of lack of D-vitamin or one of his close friends responsible for many of the building blocks of your DNA and function.